Recombinant Human Vacuolar Protein Sorting 26 Homolog A (S. pombe), His-tagged

• Cat.No.: VPS26A-6954H
• Product Overview: Recombinant human VPS26A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Specification

• Description: VPS26A is essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also this protein is required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA).
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 0.15M NaCl.
• Molecular Mass: 40.6 kDa (350aa), confirmed by MALDI-TOF
• Protein length: 1-327aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSFLGGF FGPICEIDIV LNDGETRKMA EMKTEDGKVE KHYLFYDGES VSGKVNLAFK QPGKRLEHQG IRIEFVGQIE LFNDKSNTHE FVNLVKELAL PGELTQSRSY DFEFMQVEKP YESYIGANVR LRYFLKVTIV RRLTDLVKEY DLIVHQLATY PDVNNSIKME VGIEDCLHIE FEYNKSKYHL KDVIVGKIYF LLVRIKIQHM ELQLIKKEIT GIGPSTTTET ETIAKYEIMD GAPVKGESIP IRLFLAGYDP TPTMRDVNKK FSVRYFLNLV LVDEEDRRYF KQQEIILWRK APEKLRKQRT NFHQRFESPE SQASAEQPEM
• Purity: >85% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: VPS26A vacuolar protein sorting 26 homolog A (S. pombe) [ Homo sapiens ]
• Official Symbol: VPS26A
• Synonyms: VPS26A; vacuolar protein sorting 26 homolog A (S. pombe); vacuolar protein sorting 26 (yeast homolog) , vacuolar protein sorting 26 (yeast) , vacuolar protein sorting 26 homolog A (yeast) , VPS26; vacuolar protein sorting-associated protein 26A; Hbeta58; PEP8A; vesicle protein sorting 26A; HB58; VPS26; FLJ12930
• Gene ID: 9559
• mRNA Refseq: NM_001035260
• Protein Refseq: NP_001030337
• MIM: 605506
• UniProt ID: O75436
• Chromosome Location: 10q21.1
• Function: protein binding; protein transporter activity