Recombinant Human V-Ral Simian Leukemia Viral Oncogene Homolog A (ras related), His-tagged

• Cat.No.: RALA-1777H
• Product Overview: Recombinant humanRALA protein, fused to His-tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: Human
• Tag: His
• Description: RALA (Ras-relatedprotein Ral-A) belongs to the small GTPase superfamily, Ras family ofproteins. RALA mediates a distinct downstream signaling pathway from Ras thatfacilitates cellular transformation. RALA is also thought to be involved innumerous signaling cascades, including regulation of the cytoskeleton, vesicletrafficking, and endocytosis.
• Concentration: 0.5 mg/ml
• Form: Suppliedas a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol, 2mMDTT, 100mM NaCl, and 0.1mM PMSF.
• Purity: > 90% by SDS -PAGE
• Sequence: 1-203 amino acids:MGSSHHHHHH SSGLVPRGSH MGSHMAANKP KGQNSLALHK VIMVGSGGVG KSALTLQFMY DEFVEDYEPTKADSYRKKVV LDGEEVQIDI LDTAGQEDYA AIRDNYFRSG EGFLCVFSIT EMESFAATAD FREQILRVKEDENVPFLLVG NKSDLEDKRQ VSVEEAKNRA EQWNVNYVET SAKTRANVDK VFFDLMREIR ARKMEDSKEKNGK
• Molecular Mass: 31.8 kDa(291aa), confirmed by MALDI-TOF.
• Applications: SDS-PAGE
• Storage: Storeat 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg Cor - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
• OfficialSymbol: RALA

Gene Information

• Gene Name: RALA v-ral simian leukemia viraloncogene homolog A (ras related) [ Homo sapiens ]
• Synonyms: RALA; v-ral simian leukemia viral oncogene homolog A (rasrelated); RAL; MGC48949; ras-related protein Ral-A; OTTHUMP00000158977;OTTHUMP00000207663; RAS-like protein A; Ras family small GTP binding proteinRALA
• Gene ID: 5895
• mRNA Refseq: NM_005402
• Protein Refseq: NP_005393
• MIM: 179550
• UniProt ID: P11233
• Chromosome Location: 7p15-p13
• Pathway: Arf6trafficking events; ErbB1 downstream signaling; NGF signalling via TRKA fromthe plasma membrane; Pancreatic cancer; Pathways in cancer; Signalling byNGF; Signalling to ERKs; Signalling to RAS; p38MAPK events
• Function: Edg-2lysophosphatidic acid receptor binding; GTP binding; GTPase activity;nucleotide binding; protein binding