Recombinant Human USP46 Protein, GST-His-tagged

• Cat.No.: USP46-419H
• Product Overview: Recombinant Human USP46, transcript variant 1, fused with N-terminal GST and C-terminal His was expressed in E. coli.

Specification

• Description: Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP46 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).
• Source: E. coli
• Species: Human
• Tag: His&GST
• Form: 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
• Molecular Mass: 68.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: USP46 ubiquitin specific peptidase 46 [ Homo sapiens ]
• Official Symbol: USP46
• Synonyms: USP46; ubiquitin specific peptidase 46; ubiquitin specific protease 46; ubiquitin carboxyl-terminal hydrolase 46; FLJ12552; ubiquitin thioesterase 46; deubiquitinating enzyme 46; ubiquitin thiolesterase 46; ubiquitin-specific-processing protease 46; FLJ11850; FLJ14283; FLJ39393
• Gene ID: 64854
• mRNA Refseq: NM_001134223
• Protein Refseq: NP_001127695
• MIM: 612849
• UniProt ID: P62068