Recombinant Human UPRT protein, His & GST-tagged

• Cat.No.: UPRT-1435H
• Product Overview: Recombinant Human UPRT aa. (Asn75~Ala297 (Accession # Q96BW1)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Description: This gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer.
• Source: E. coli
• Species: Human
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 51.8kDa
• Protein length: Asn75~Ala297
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 6.2

Gene Information

• Gene Name: UPRT uracil phosphoribosyltransferase homolog [ Homo sapiens (human) ]
• Official Symbol: UPRT
• Synonyms: UPRT; uracil phosphoribosyltransferase homolog; UPP; FUR1; uracil phosphoribosyltransferase homolog; RP11-311P8.3; UMP pyrophosphorylase; UPRTase; uracil phosphoribosyltransferase (FUR1) homolog
• Gene ID: 139596
• mRNA Refseq: NM_145052.3
• Protein Refseq: NP_659489.1
• UniProt ID: Q96BW1