Recombinant Human UNC5B Protein, His-tagged

• Cat.No.: UNC5B-556H
• Product Overview: Recombinant human UNC5B (NP_734465.2) (Met1-Pro363) was expressed with a polyhistidine tag at the C-terminus.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: 1-363 a.a.
• Predicted N Terminal: Gly 27
• Form: Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol.
• Molecular Mass: The recombinant human UNC5B consists 348 amino acids and predicts a molecular mass of 39.2 kDa.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >95 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
• Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: UNC5B unc-5 homolog B (C. elegans) [ Homo sapiens ]
• Official Symbol: UNC5B
• Synonyms: UNC5B; unc-5 homolog B (C. elegans); unc5 (C.elegans homolog) b; netrin receptor UNC5B; p53RDL1; UNC5H2; unc-5 homolog 2; protein unc-5 homolog 2; protein unc-5 homolog B; transmembrane receptor Unc5H2; p53-regulated receptor for death and life protein 1
• Gene ID: 219699
• mRNA Refseq: NM_001244889
• Protein Refseq: NP_001231818
• MIM: 607870
• UniProt ID: Q8IZJ1
• Chromosome Location: 10q22.2
• Pathway: Apoptosis, organism-specific biosystem; Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Netrin mediated repulsion signals, organism-specific biosystem; Netrin-1 signaling, organism-specific biosystem