Recombinant Human UNC5B Protein, MYC/DDK-tagged

• Cat.No.: UNC5B-634H
• Product Overview: Recombinant human UNC5B protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011].
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 103.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: unc-5 netrin receptor B[ Homo sapiens ]
• Official Symbol: UNC5B
• Synonyms: p53RDL1; UNC5H2
• Gene ID: 219699
• mRNA Refseq: NM_170744.3
• Protein Refseq: NP_734465.2
• MIM: 607870
• UniProt ID: Q8IZJ1