Recombinant Human UNC13A Protein, 1000-1703, His-tagged

• Cat.No.: UNC13A-02H
• Product Overview: Recombinant Human UNC13A Protein, 1000-1703, with His-tag was purified from HEK293

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: 1000-1703
• Description: This gene encodes a member of the UNC13 family. UNC13 proteins bind to phorbol esters and diacylglycerol and play important roles in neurotransmitter release at synapses. Single nucleotide polymorphisms in this gene may be associated with sporadic amyotrophic lateral sclerosis.
• Molecular Mass: Theoretical molecular weight: ~ 97 kDa
• AA Sequence: MHHHHHHVKACLNSTYEYIFNNCHELYSREYQTDPAKKGEVLPEEQGPSIKNLDFWSKLITLIVSIIEEDKNSYTPCLNQFPQELNVGKISAEVMWNLFAQDMKYAMEEHDKHRLCKSADYMNLHFKVKWLYNEYVTELPAFKDRVPEYPAWFEPFVIQWLDENEEVSRDFLHGALERDKKDGFQQTSEHALFSCSVVDVFSQLNQSFEIIKKLECPDPQIVGHYMRRFAKTISNVLLQYADIISKDFASYCSKEKEKVPCILMNNTQQLRVQLEKMFEAMGGKELDAEASDILKELQVKLNNVLDELSRVFATSFQPHIEECVKQMGDILSQVKGTGNVPASACSSVAQDADNVLQPIMDLLDSNLTLFAKICEKTVLKRVLKELWKLVMNTMEKTIVLPPLTDQTMIGNLLRKHGKGLEKGRVKLPSHSDGTQMIFNAAKELGQLSKLKDHMVREEAKSLTPKQCAVVELALDTIKQYFHAGGVGLKKTFLEKSPDLQSLRYALSLYTQATDLLIKTFVQTQSAQGLGVEDPVGEVSVHVELFTHPGTGEHKVTVKVVAANDLKWQTSGIFRPFIEVNIIGPQLSDKKRKFATKSKNNSWAPKYNESFQFTLSADAGPECYELQVCVKDYCFAREDRTVGLAVLQLRELAQRGSAACWLPLGRRIHMDDTGLTVLRILSQRSNDEVAKEFVKLKSDTRSAEEGGAAPAP
• Endotoxin: < 1 EU/μg protein by LAL
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.05 mg/mL
• Storage Buffer: PBS buffer, pH 7.4

Gene Information

• Gene Name: UNC13A unc-13 homolog A (C. elegans) [ Homo sapiens (human) ]
• Official Symbol: UNC13A
• Synonyms: UNC13A; unc-13 homolog A (C. elegans); protein unc-13 homolog A; KIAA1032; Munc13 1; Munc13-1
• Gene ID: 23025
• mRNA Refseq: NM_001080421
• Protein Refseq: NP_001073890
• MIM: 609894
• UniProt ID: Q9UPW8