Recombinant Human UNC119 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: UNC119-5865H
• Product Overview: UNC119 MS Standard C13 and N15-labeled recombinant protein (NP_473376) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene is specifically expressed in the photoreceptors in the retina. The encoded product shares strong homology with the C. elegans unc119 protein and it can functionally complement the C. elegans unc119 mutation. It has been localized to the photoreceptor synapses in the outer plexiform layer of the retina, and suggested to play a role in the mechanism of photoreceptor neurotransmitter release through the synaptic vesicle cycle. Two transcript variants encoding different isoforms have been described for this gene.
• Molecular Mass: 23.9 kDa
• AA Sequence: MKVKKGGGGAGTATESAPGPSGQSVAPIPQPPAESESGSESEPDAGPGPRPGPLQRKQPIGPEDVLGLQRITGDYLCSPEENIYKIDFVRFKIRDMDSGTVLFEIKKPPVSERLPINRRDLDPNAGRFVRYQFTPAFLRLRQVGATVEFTVGDKPVNNFRMIERHYFRNQLLKSFDFHFGFCIPSSKNTCEHIYDFPPLSEELSARAGSSGSGEVGASRDTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: UNC119 unc-119 lipid binding chaperone [ Homo sapiens (human) ]
• Official Symbol: UNC119
• Synonyms: UNC119; unc-119 homolog; unc119 (C.elegans) homolog; protein unc-119 homolog A; HRG4; POC7; POC7 centriolar protein homolog A (Chlamydomonas); POC7A; retinal protein 4; POC7 centriolar protein homolog A
• Gene ID: 9094
• mRNA Refseq: NM_054035
• Protein Refseq: NP_473376
• MIM: 618925
• UniProt ID: Q13432