Recombinant Human UMPS Protein, His-tagged
Cat.No. : | UMPS-212H |
Product Overview : | Recombinant Human UMPS(1-480aa) fused with His tag at C-terminal was expressed in Insect cells. |
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Species : | Human |
Source : | Insect Cells |
Tag : | His |
Protein Length : | 1-480aa |
Description : | UMPS, also known as uridine 5'-monophosphate synthase, is a bifunctional enzyme catalyzing the last two steps of de novo pyrimidine biosynthesis. It is an indispensable component in this metabolic pathway and is a target for antimalarial and antitumor drugs. Its expression in colorectal carcinoma tissues is not correlated with the toxicities of 5-FU-based regimen, but It in the normal tissues can help predict the toxicities associated with 5-FU. |
Form : | Liquid. In Phosphate Buffered Saline (pH 7.4). |
Molecular Mass : | 53kDa (486aa) 50-70kDa (SDS-PAGE under reducing conditions) |
AA Sequence : | MAVARAALGP LVTGLYDVQA FKFGDFVLKS GLSSPIYIDL RGIVSRPRLL SQVADILFQT AQNAGISFDT VCGVPYTALP LATVICSTNQ IPMLIRRKET KDYGTKRLVE GTINPGETCL IIEDVVTSGS SVLETVEVLQ KEGLKVTDAI VLLDREQGGK DKLQAHGIRL HSVCTLSKML EILEQQKKVD AETVGRVKRF IQENVFVAAN HNGSPLSIKE APKELSFGAR AELPRIHPVA SKLLRLMQKK ETNLCLSADV SLARELLQLA DALGPSICML KTHVDILNDF TLDVMKELIT LAKCHEFLIF EDRKFADIGN TVKKQYEGGI FKIASWADLV NAHVVPGSGV VKGLQEVGLP LHRGCLLIAE MSSTGSLATG DYTRAAVRMA EEHSEFVVGF ISGSRVSMKP EFLHLTPGVQ LEAGGDNLGQ QYNSPQEVIG KRGSDIIIVG RGIISAADRL EAAEMYRKAA WEAYLSRLGV HHHHHH |
Purity : | > 95% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.25mg/ml (determined by Absorbance at 280nm) |
Gene Name | UMPS uridine monophosphate synthetase [ Homo sapiens ] |
Official Symbol | UMPS |
Synonyms | UMPS; uridine monophosphate synthetase; uridine 5-monophosphate synthase; orotate phosphoribosyl transferase and orotidine 5 decarboxylase; OPRTase; OMPdecase; UMP synthase; orotate phosphoribosyltransferase; orotidine 5-phosphate decarboxylase; OPRT; |
Gene ID | 7372 |
mRNA Refseq | NM_000373 |
Protein Refseq | NP_000364 |
MIM | 613891 |
UniProt ID | P11172 |
◆ Recombinant Proteins | ||
UMPS-3595H | Recombinant Human UMPS, His-tagged | +Inquiry |
UMPS-349H | Recombinant Human uridine monophosphate synthetase, His-tagged | +Inquiry |
UMPS-10520Z | Recombinant Zebrafish UMPS | +Inquiry |
UMPS-4917R | Recombinant Rhesus Macaque UMPS Protein, His (Fc)-Avi-tagged | +Inquiry |
Umps-6834M | Recombinant Mouse Umps Protein, Myc/DDK-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
UMPS-503HCL | Recombinant Human UMPS 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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