Recombinant Human ULK4, GST-tagged

• Cat.No.: ULK4-7028H
• Product Overview: Recombinant human ULK4 (1-616) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Protein Length: 1-616 aa
• Description: ULK4, or Unc-51-like kinase 4, is a Ser/Thr protein kinase that is a member of the APG1/unc-51/ULK1 subfamily. ULK4 contains five HEAT repeats and a catalytic kinase domain. The ULK4 gene is conserved in many species including chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, A.thaliana, and rice. ULK4 has been implicated as a gene involved in the development of hydrocephalus. This neurologic disorder in animal models is being used to elucidate factors responsible for the excessive accumulation of cerebrospinal fluid in hydrocephalic humans.
• Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: ~97 kDa
• Purity: >75%
• Applications: Western Blot
• Storage: Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
• Concentration: 0.1 μg/μl

Gene Information

• Gene Name: ULK4 unc-51-like kinase 4 (C. elegans) [ Homo sapiens ]
• Official Symbol: ULK4
• Synonyms: ULK4; unc-51-like kinase 4 (C. elegans); serine/threonine-protein kinase ULK4; FAM7C1; FLJ20574; REC01035; DKFZp434E1822
• Gene ID: 54986
• mRNA Refseq: NM_017886
• Protein Refseq: NP_060356
• UniProt ID: Q96C45
• Chromosome Location: 3p22.1
• Function: ATP binding; binding; nucleotide binding; protein serine/threonine kinase activity