Recombinant Human UL16 binding protein 1 Protein, His tagged

• Cat.No.: ULBP1-270H
• Product Overview: Recombinant human ULBP1/NKG2DL1 protein (Q9BZM6) (Gly 26-Gly 216) with a His tag at the C-terminus was expressed in HEK293.

Specification

• Description: The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: C-His
• Protein length: 26-216aa
• Molecular Mass: 23.7 kDa
• Endotoxin: Less than 1.0 EU/μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
• Reconstitution: Reconstitute at 250 μg/mL in sterile water.

Gene Information

• Gene Name: ULBP1 UL16 binding protein 1 [ Homo sapiens (human) ]
• Official Symbol: ULBP1
• Synonyms: ULBP1; UL16 binding protein 1; NKG2D ligand 1; RAET1I; N2DL-1; NKG2DL1; alcan-beta; UL16-binding protein 1; retinoic acid early transcript 1I
• Gene ID: 80329
• mRNA Refseq: NM_025218
• Protein Refseq: NP_079494
• MIM: 605697
• UniProt ID: Q9BZM6