Recombinant Human UBQLN3 Protein, His-tagged

• Cat.No.: UBQLN3-490H
• Product Overview: Recombinant Human UBQLN3 fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: THis gene encodes a ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and are thus thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. THis gene is specifically expressed in the testis. It has been suggested that tHis gene may regulate cell-cycle progression during spermatogenesis, however, it has been shown that the ortholgous mouse gene is dispensable for embryonic development and spermatogenesis.
• Form: 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
• Molecular Mass: 70.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: UBQLN3 ubiquilin 3 [ Homo sapiens ]
• Official Symbol: UBQLN3
• Synonyms: TUP-1
• Gene ID: 50613
• mRNA Refseq: NM_017481.2
• Protein Refseq: NP_059509.1
• MIM: 605473
• UniProt ID: Q9H347