Recombinant Human UBE4A Protein, MYC/DDK-tagged

• Cat.No.: UBE4A-480H
• Product Overview: Recombinant human UBE4A protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 123.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: ubiquitination factor E4A[ Homo sapiens ]
• Official Symbol: UBE4A
• Synonyms: E4; UBOX2; UFD2
• Gene ID: 9354
• mRNA Refseq: NM_001204077.1
• Protein Refseq: NP_001191006.1
• MIM: 603753
• UniProt ID: Q14139