Recombinant Human UBE2V2, His-tagged

• Cat.No.: UBE2V2-210H
• Product Overview: Recombinant human UBE2V2 (2-end) was expressed in E. coli cells using an N-terminal His tag.

Specification

• Description: UBE2V2 or ubiquitin-conjugating enzyme E2 variant 2 constitutes a distinct subfamily within the E2 protein family which is critical for the catalytic activity of E2s and also shares homology with ubiquitin-conjugating enzyme E2 variant 1 and yeast MMS2 gene product. UBE2V2 may be involved in the differentiation of monocytes and enterocytes. UBE2V2 functions in assembly of novel polyubiquitin chains for DNA repair.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Recombinant protein stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
• Molecular Mass: ~18 kDa
• Purity: >95% by densitometry
• Applications: Western Blot
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1 μg/μl
• Protein length: 2-end a.a.

Gene Information

• Gene Name: UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 [ Homo sapiens ]
• Official Symbol: UBE2V2
• Synonyms: UBE2V2; ubiquitin-conjugating enzyme E2 variant 2; DDVit 1; EDPF 1; MMS2; UEV 2; MMS2 homolog; vitamin D3-inducible protein; 1 alpha,25-dihydroxyvitamin D3-inducible; enterocyte differentiation promoting factor; enterocyte differentiation-promoting factor 1; enterocyte differentiation-associated factor 1; enterocyte differentiation-associated factor EDAF-1; methyl methanesulfonate sensitive 2, S. cerevisiae, homolog of; UEV2; EDPF1; UEV-2; DDVIT1; EDAF-1; EDPF-1; DDVit-1
• Gene ID: 7336
• mRNA Refseq: NM_003350
• Protein Refseq: NP_003341
• MIM: 603001
• UniProt ID: Q15819
• Chromosome Location: 8q11.21
• Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem
• Function: acid-amino acid ligase activity; protein binding