UBE2V2

  • Official Full Name

    ubiquitin-conjugating enzyme E2 variant 2

  • Overview

    Ubiquitin-conjugating enzyme E2 variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene also shares homology with ubiquitin-conjugating enzyme E2 variant 1 and yeast MMS2 gene product. It may be involved in the differentiation of monocytes and enterocytes.

  • Synonyms

    UBE2V2;ubiquitin-conjugating enzyme E2 variant 2;DDVit 1;EDPF 1;MMS2;UEV 2;1 alpha 25 dihydroxyvitamin D3 inducible;1 alpha 25-dihydroxyvitamin D3 inducible;DDVIT1;EDAF-1;EDAF1;EDPF-1;EDPF1;Enterocyte differentiation associated factor EDAF 1;Enterocyte differentiation promoting factor;Enterocyte differentiation-associated factor 1;Enterocyte differentiation-promoting factor 1;Methyl methanesulfonate sensitive 2;MMS 2;MMS2 homolog;UB2V2_HUMAN;UBE2V 2;Ubiquitin conjugating enzyme E2 variant 2;Ubiquitin conjugating enzyme E2v2;UEV2;Vitamin D3 inducible protein;Vitamin D3-inducible protein;1 alpha,25-dihydroxyvitamin D3-inducible;enterocyte differentiation-associated factor EDAF-1;methyl methanesulfonate sensitive 2, S. cerevisiae, homolog of;UEV-2;DDVit-1

Recombinant Proteins

  • Zebrafish
  • Human
  • Mouse
  • Chicken
  • Rhesus macaque
  • Mammalian Cells
  • E.coli
  • HEK293
  • Insect Cells
  • His
  • Non
  • Strep
  • SUMO
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
UBE2V2-12674Z Recombinant Zebrafish UBE2V2 Mammalian Cells Zebrafish His
UBE2V2-143H Recombinant Human UBE2V2 E.coli Human Non
UBE2V2-17736M Recombinant Mouse UBE2V2 Protein Mammalian Cells Mouse His
UBE2V2-210H Recombinant Human UBE2V2, His-tagged E.coli Human His 2-end a.a.
UBE2V2-2699C Recombinant Chicken UBE2V2 Mammalian Cells Chicken His
UBE2V2-30036TH Recombinant Human UBE2V2, His-tagged E.coli Human His 145 amino acids
UBE2V2-5069R Recombinant Rhesus monkey UBE2V2 Protein, His-tagged Mammalian Cells Rhesus macaque His
UBE2V2-60H Recombinant Human UBE2V2, His-tagged E.coli Human His 1-145 aa
UBE2V2-559HCL Recombinant Human UBE2V2 293 Cell Lysate HEK293 Human Non
UBE2V2-0521H Recombinant Human UBE2V2 Protein (A2-N145), Tag Free Insect Cells Human Non A2-N145
UBE2V2-0522H Recombinant Human UBE2V2 Protein (A2-N145), His/Strep tagged Insect Cells Human His&Strep A2-N145
UBE2V2-3644H Recombinant Human UBE2V2 protein, His-SUMO-tagged E.coli Human His&SUMO 2-145aa
UBE2V2-4882R Recombinant Rhesus Macaque UBE2V2 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
UBE2V2-4882R-B Recombinant Rhesus Macaque UBE2V2 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
UBE2V2-9840M Recombinant Mouse UBE2V2 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
UBE2V2-9840M-B Recombinant Mouse UBE2V2 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    UBE2V2 involved in several pathways and played different roles in them. We selected most pathways UBE2V2 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &amp,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBE2V2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    DNA Repair COPS4,KIAA0146,TP53BP1,TOPBP1,TDP1,SMARCA5,PNKP,BARD1,ZNF830,APITD1
    Proteasome degradation RNF123,LRRC41,SPSB2,RNF4,GAN,RNF144B,UBE2V1,TRIM9,RNF182,ASB17
    DNA Double-Strand Break Repair BRCC3,CLSPN,RBBP8,KDM4B,HUS1,RHNO1,RAD50,GEN1,RAD17,POLD3
    Cell Cycle Checkpoints UIMC1,CHEK2,RAD9A,BRCC3,RAD17,CLSPN,RAD9B,FAM175A,RAD50,THRSP
    Class I MHC mediated antigen processing &amp UBR1,UBA5,SEC61B,TRAF7,UBE2E3,CYBB,ERAP1,ASB2,KLHL20,NPEPPS
    Antigen processing: Ubiquitination &amp ARIH2,UBR2,SPSB4,RNF25,UBE2E3,KLHL20,UBE2L6,FBXO3,RNF4,RNF14
    presentation UBE2L6,ASB17,ARIH2,ASB2,VPRBP,SEC61B,LRRC41,RBCK1,UBA5,B2ML
    Adaptive Immune System CDKN1B,RNF182,CTSB,TRAT1,RAPGEF4,SPTBN2,BTLA,TRAF7,AHCYL1,MICA
    Cell cycle DCTN1A,NEK7,DHFR,PIANP,DBF4,SPDL1,YWHAZ,CDC27,ITGB3BP,PTTG2

    Protein Function

    UBE2V2 has several biochemical functions, for example, protein binding,ubiquitin conjugating enzyme activity,ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UBE2V2 itself. We selected most functions UBE2V2 had, and list some proteins which have the same functions with UBE2V2. You can find most of the proteins on our site.

    Function Related Protein
    ubiquitin protein ligase binding UBE2T,EIF4E2,TRAF6,MAGEA2,ACTG1,JAK1,MAP1LC3B,PIAS2,PRKAR2A,GABARAPL1
    ubiquitin conjugating enzyme activity UBE2H,UBE2Z,UBE2D1,UBE2Q1,UBE2L3,UBE2Q2,UBE2O,UBE2E3,UBE2N,UBE2D3
    ubiquitin protein ligase activity ARIH1L,CCNC,SIAH1,UBE2J2,STUB1,UBR3,TRIM6,UBE2T,FBXO30,MSL2A
    protein binding ABLIM1,SYNJ2,WDYHV1,TMPRSS15,ZFHX3,KLHL35,ATF7IP,POLA1,SUSD2,MAP2K1

    Interacting Protein

    UBE2V2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBE2V2 here. Most of them are supplied by our site. Hope this information will be useful for your research of UBE2V2.

    UBE2N;UBC35;EIF1B;TRAF6;EGFR;RNF144A;USP14;XIAP;MKRN3;SNTA1;RIF1;DZIP3;SIAH1;ZNRF1;MALSU1;IGSF21

    Resources

    Research Area

    DNA Damage and Repair
    E2 Ubiquitin/Ubl Conjugating Enzymes
    Post-translational Modification of NFkB/IkB

    References

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