Recombinant Human UBE2T Protein (Q2-V197), His/Strep tagged

• Cat.No.: UBE2T-0014H
• Product Overview: Recombinant Human 8His-StrepII-TEV-(GG)-UBE2T(Q2-V197 end) Protein was expressed in Insect cell.

Specification

• Description: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induced DNA repair. Acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCL and FANCI. May contribute to ubiquitination and degradation of BRCA1. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11'-, 'Lys-27'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination.
• Source: Insect cell
• Species: Human
• Tag: His&Strep
• Form: Liquid
• Protein length: Q2-V197
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: UBE2T ubiquitin-conjugating enzyme E2T (putative) [ Homo sapiens (human) ]
• Official Symbol: UBE2T
• Synonyms: UBE2T; ubiquitin-conjugating enzyme E2T (putative); ubiquitin-conjugating enzyme E2 T; HSPC150; ubiquitin-protein ligase T; ubiquitin carrier protein T; ubiquitin conjugating enzyme; cell proliferation-inducing gene 50 protein; HSPC150 protein similar to ubiquitin-conjugating enzyme; PIG50
• Gene ID: 29089
• mRNA Refseq: NM_014176
• Protein Refseq: NP_054895
• MIM: 610538
• UniProt ID: Q9NPD8