Recombinant Human TXN Protein (M1-V105), His/Strep tagged

• Cat.No.: TXN-0808H
• Product Overview: Recombinant Human 6His-strepII-TEV-GG-TXN(M1-V105 end) Protein was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His&Strep
• Protein Length: M1-V105
• Description: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity ().
• Form: Liquid
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: TXN thioredoxin [ Homo sapiens (human) ]
• Official Symbol: TXN
• Synonyms: TXN; thioredoxin; TRX; ADF; SASP; TXN delta 3; ATL-derived factor; thioredoxin delta 3; surface-associated sulphydryl protein; TRDX; TRX1; MGC61975; DKFZp686B1993
• Gene ID: 7295
• mRNA Refseq: NM_001244938
• Protein Refseq: NP_001231867
• MIM: 187700
• UniProt ID: P10599