Recombinant Human TXN, His-tagged

• Cat.No.: TXN-31511TH
• Product Overview: Recombinant full length Human Thioredoxin / TRX protein fused to a 6X His tag at the N terminus, Amino acids 1-105, molecular weight: 14 kDa

Specification

• Description: The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene.
• Conjugation: HIS
• Source: E. coli
• Biological activity: Specific activity is 7-10 A650/min/mg, obtained by measuring the increase of insulin precipitation in absorbance at 650 nm resulting from the reduction of insulin.
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: PBS, pH 7.4
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Store in the dark. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Belongs to the thioredoxin family.Contains 1 thioredoxin domain.
• Protein length: 1-105 a.a.
• Full Length: Full L.

Gene Information

• Gene Name: TXN thioredoxin [ Homo sapiens ]
• Official Symbol: TXN
• Synonyms: TXN; thioredoxin; TRX
• Gene ID: 7295
• mRNA Refseq: NM_001244938
• Protein Refseq: NP_001231867
• MIM: 187700
• Uniprot ID: P10599
• Chromosome Location: 9q31
• Pathway: Folic Acid Network, organism-specific biosystem; Folic Acid Network, organism-specific biosystem; Immune System, organism-specific biosystem; Inflammasomes, organism-specific biosystem; Innate Immune System, organism-specific biosystem
• Function: electron carrier activity; peptide disulfide oxidoreductase activity; protein binding; protein disulfide oxidoreductase activity