Recombinant Human Tumor Necrosis Factor Receptor Superfamily, Member 13C
Cat.No. : | TNFRSF13C-5255H |
Product Overview : | Recombinant human TNFRSF13C is adisulfide-linked monomeric protein consisting of 76 amino acid residuesubunits. The molecule has a calculated molecular mass of approximately 9 kDaand migrates as an approximately 9 kDa protein under non-reducing andreducing conditions in SDS-PAGE. |
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Species : | Human |
Source : | Human |
Tag : | Non |
Description : | TNFRSF13C appears to be particularly important for the regulation of Bcell survival and maturation in the spleen, because A/WySnJ mice expressing adefective TNFRSF13C have disrupted B cell maturation, similar to that seen inBAFF-deficient mice. |
Form : | RecombinantTNFRSF13C was lyophilized from a 0.2 μm filtered solution in 2.5%glycine, 0.5% sucrose, 0.01% Tween80, 5 mM Glutamic acid, pH 4.5. |
Purity : | >95%, asdetermined by SDS-PAGE and HPLC. |
Sequence : | MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPGLL |
Molecular Weight : | 9 kDa. |
Biological Activity : | TheED(50) was determined by the ability to block BAFF induced survival ofsplenocyte cells, and was found to be in the range of 1.0-5.0 ug/ml. |
Endotoxin : | Less than 0.1 ng/µg (1EU/µg). |
Reconstitution : | A quick spin of thevial followed by reconstitution in distilled water to a concentration notless than 0.1 mg/ml. This solution can then be diluted into other buffers. |
Storage : | The lyophilizedprotein is stable for at least 2 years from date of receipt at -20°C. Uponreconstitution, this cytokine can be stored in working aliquots at 2°C - 8°Cfor one month, or at -20°C for six months, with a carrier protein withoutdetectable loss of activity. Avoid repeated freeze/thaw cycles. |
OfficialSymbol : | TNFRSF13C |
Pathways : | Cytokine-cytokine receptorinteraction |
Gene Name | TNFRSF13C tumor necrosisfactor receptor superfamily, member 13C [ Homo sapiens ] |
Synonyms | TNFRSF13C; tumor necrosisfactor receptor superfamily, member 13C; CD268; MGC138235; BAFF receptor;OTTHUMP00000028746; B cell-activating factor receptor; BAFF-R; BAFFR; BR3;BLyS receptor 3; CD268 antigen; tumor necrosis factor receptor superfamily,member 13C |
Gene ID | 115650 |
mRNA Refseq | NM_052945 |
Protein Refseq | NP_443177 |
MIM | 606269 |
UniProt ID | Q5H8V1 |
Chromosome Location | 22q13.1-q13.31 |
Function | receptor activity |
◆ Recombinant Proteins | ||
TNFRSF13C-551H | Active Recombinant Human TNFRSF13C, Fc-tagged, Biotinylated | +Inquiry |
TNFRSF13C-1146R | Recombinant Rat TNFRSF13C protein(Ser10-Ala71), His-tagged | +Inquiry |
TNFRSF13C-25M | Recombinant Mouse BAFF-R, HIgG1, Fc-tagged | +Inquiry |
TNFRSF13C-2910H | Active Recombinant Human TNFRSF13C protein, Fc-tagged | +Inquiry |
TNFRSF13C-120H | Recombinant Human TNFRSF13C protein, hFc-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
TNFRSF13C-831RCL | Recombinant Rat TNFRSF13C cell lysate | +Inquiry |
TNFRSF13C-1861MCL | Recombinant Mouse TNFRSF13C cell lysate | +Inquiry |
Not For Human Consumption!
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