Recombinant Human TSPO, MYC/DDK-tagged

• Cat.No.: TSPO-51H
• Product Overview: Recombinant Human TSPO fused with C-terminal MYC/DDK, was expressed in HEK293 Cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein.
• Molecular Mass: 18.6 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Storage buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
• Concentration: > 50 ug/ml as determined by BCA
• Storage: Store at -80oC. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
• OfficialSymbol: TSPO

Gene Information

• Gene Name: TSPO translocator protein (18kDa) [ Homo sapiens ]
• Synonyms: TSPO; translocator protein (18kDa); benzodiazapine receptor (peripheral) , BZRP; translocator protein; DBI; IBP; MBR; mDRC; PBR; peripheral type benzodiazepine receptor/recognition site; pk18; PKBS; mitochondrial benzodiazepine receptor; benzodiazepine peripheral binding site; peripheral-type benzodiazepine receptor; PBS; BPBS; BZRP; PTBR
• Gene ID: 706
• mRNA Refseq: NM_000714
• Protein Refseq: NP_000705
• MIM: 109610
• UniProt ID: P30536
• Chromosome Location: 22q13.31
• Pathway: HTLV-I infection; Neuroactive ligand-receptor interaction
• Function: androgen binding; benzodiazepine receptor activity; cholesterol binding