Recombinant Human TNFSF13B, His-tagged

• Cat.No.: TNFSF13B-184H
• Product Overview: Recombinant human BLyS, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 21 kDa (190 aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: B lymphocyte stimulator (BLyS), a member of the tumor necrosis factor (TNF) superfamily of cytokines, induces B-cell proliferation and immunoglobulin secretion and is a key regulator of peripheral B-cell populations in vivo.BLyS is made by immune-cells called monocytes and macrophages. When monocytes and macrophages are activated, BLyS is released and binds to a receptor found only on B cells.
• Amino Acid Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMAV QGPEETVTQD CLQLIADSET PTIQKGSYTF VPWLLSFKRG SALEEKENKI LVKETGYFFI YGQVLYTDKT YAMGHLIQRK KVHVFGDELS LVTLFRCIQN MPETLPNNSC YSAGIAKLEE GDELQLAIPR ENAQISLDGD VTFFGALKLL.
• Form: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 5 mM DTT.
• Purity: > 95% by SDS – PAGE.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b [ Homo sapiens ]
• Synonyms: TNFSF13B; tumor necrosis factor (ligand) superfamily, member 13b; DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNFSF20; TNFSF13B; Tumor necrosis factor ligand superfamily member 13B; TNF- and APOL-related leukocyte expressed ligand 1; B lymphocyte stimulator; B cell-activating factor; Dendritic cell-derived TNF-like moleculeCD_antigen=CD257; Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form
• Gene ID: 10673
• mRNA Refseq: NM_001145645
• Protein Refseq: NP_001139117
• MIM: 603969
• UniProt ID: Q9Y275
• Chromosome Location: q32-q34
• Pathway: tokine-cytokine receptor interaction
• Function: cytokine activity; tumor necrosis factor receptor binding