Recombinant Human TNFRSF8 Protein, C-6His-Avi tagged, Biotinylated

Cat.No. : TNFRSF8-08H
Product Overview : Biotinylated Recombinant Human Epithelial Cell Adhesion Molecule is produced by our Mammalianexpression system and the target gene encoding Gln24-Lys265(Met115Thr) is expressed with a 6His, Avitag at the C-terminus.
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Description : CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody responses. CD30 is expressed by activated, but not by resting, T and B cells. Aberrant expression of CD30 by mastocytosis mast cells and interaction with its ligand CD30L (CD153) appears to play an important role in the pathogenesis and clinical presentation of systemic mastocytosis. CD30 has been considered as a specific diagnostic biomarker of anaplastic large cell lymphoma (ALCL) and classical Hodgkin lymphoma (cHL). CD30 is also a biomarker used for targeted therapy by an antibody–drug conjugate.
Source : Human Cells
Species : Human
Tag : His&Avi
Protein length : Gln24-Lys265(Met115Thr)
Endotoxin : Less than 0.1 ng/μg (1 EU/μg)
Storage Buffer : Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mMNaCl, pH7.4.
Shipping : Ambient
Gene Name TNFRSF8 TNF receptor superfamily member 8 [ Homo sapiens (human) ]
Official Symbol TNFRSF8
Synonyms Tumor necrosis factor receptor superfamily member 8; CD30L receptor; Ki-1 antigen; Lymphocyte activation antigen CD30; CD30; TNFRSF8
Gene ID 943
mRNA Refseq NM_001243
Protein Refseq NP_001234
MIM 153243
UniProt ID P28908

Not For Human Consumption!

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