Recombinant Human TNFRSF17, His-tagged

• Cat.No.: TNFRSF17-7060H
• Product Overview: Recombinant human TNFRSF17 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: Tumor necrosis factor receptor superfamily member 17, also known as TNFRSF17, is a member of the TNF-receptor superfamily. The open reading frame of the gene encoding TNFRSF17 predicts a 184 amino acid protein with a single transmembrane domain that has no homology with any known protein sequences. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. TNFRSF17 also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl,10% glycerol,1mM DTT
• Molecular Mass: 14.1 kDa (130aa)
• Protein length: 78-184 aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSRKINSEP LKDEFKNTGS GLLGMANIDL EKSRTGDEII LPRGLEYTVE ECTCEDCIKS KPKVDSDHCFPLPAMEEGAT ILVTTKTNDY CKSLPAALSA TEIEKSISAR
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml

Gene Information

• Gene Name: TNFRSF17 tumor necrosis factor receptor superfamily, member 17 [ Homo sapiens ]
• Official Symbol: TNFRSF17
• Synonyms: TNFRSF17; tumor necrosis factor receptor superfamily, member 17; BCMA; tumor necrosis factor receptor superfamily member 17; BCM; CD269; B-cell maturation factor; B cell maturation antigen; B-cell maturation protein
• Gene ID: 608
• mRNA Refseq: NM_001192
• Protein Refseq: NP_001183
• MIM: 109545
• UniProt ID: Q02223
• Chromosome Location: 16p13.1
• Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Intestinal immune network for IgA production, organism-specific biosystem; Intestinal immune network for IgA production, conserved biosystem
• Function: receptor activity; tumor necrosis factor-activated receptor activity