Recombinant Human TMPRSS2 Protein (Ser284-Gly492), His tagged
Cat.No. : | TMPRSS2-6469H |
Product Overview : | Recombinant human TMPRSS2 (Ser284-Gly492) fused with His tag was expressed in E. coli. |
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Species : | Human |
Source : | E.coli |
Tag : | His |
Protein Length : | Ser284-Gly492 |
Description : | Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption and metastasis of prostate cancer cells. In addition, activates trigeminal neurons and contribute to both spontaneous pain and mechanical allodynia. |
Form : | Lyophilized powder/frozen liquid |
Molecular Mass : | 23.94 kDa |
Purity : | > 90 % as determined by SDS-PAGE |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5. |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name | TMPRSS2 transmembrane protease, serine 2 [ Homo sapiens (human) ] |
Official Symbol | TMPRSS2 |
Synonyms | TMPRSS2; transmembrane protease, serine 2; transmembrane protease serine 2; PRSS10; epitheliasin; serine protease 10; PP9284; FLJ41954; |
Gene ID | 7113 |
mRNA Refseq | NM_001135099 |
Protein Refseq | NP_001128571 |
MIM | 602060 |
UniProt ID | O15393 |
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Not For Human Consumption!
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