Recombinant Human TMEM27 protein, His-tagged

• Cat.No.: TMEM27-1782H
• Product Overview: Recombinant Human TMEM27 aa. (Cys17~Asp137 (Accession # Q9HBJ8)) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Cys17~Asp137
• Description: This gene encodes a type 1 transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. The encoded protein binds to amino acid transporters and regulates their expression on the plasma membrane. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. The extracellular domain of the encoded protein may be cleaved and shed from the plasma membrane specifically in pancreatic beta cells.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 15.3kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 1mM DTT, 5% trehalose, 0.01% sarcosyl and preservative.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 7.9

Gene Information

• Gene Name: TMEM27 transmembrane protein 27 [ Homo sapiens (human) ]
• Official Symbol: TMEM27
• Synonyms: TMEM27; transmembrane protein 27; NX17; NX-17; collectrin; kidney-specific membrane protein
• Gene ID: 57393
• mRNA Refseq: NM_020665.5
• Protein Refseq: NP_065716.1
• UniProt ID: Q9HBJ8