Recombinant Human TLR5 protein, Fc-tagged

• Cat.No.: TLR5-392H
• Product Overview: Recombinant Human TLR5(aa 21-639) fused with Fc region of human IgG1 at N-terminal was expressed in CHO cells.

Specification

• Species: Human
• Source: CHO
• Tag: Fc
• Protein Length: 21-639 a.a.
• Form: 0.2 µm filtered solution in phosphate buffer with glycine, saccharose and stabilizing agents
• Molecular Mass: Has an apparent molecular weight of 110 kDa on SDS-PAGE.
• Applications: Neutralization, receptor binding assays
• Storage: Store lyophilized product at -20 centigrade. Product is stable for at least 1 year.

Gene Information

• Gene Name: TLR5 toll-like receptor 5 [ Homo sapiens ]
• Official Symbol: TLR5
• Synonyms: TLR5; toll-like receptor 5; FLJ10052; MGC126430; MGC126431; SLEB1; TIL3; Toll/interleukin 1 receptor like protein 3; toll/interleukin-1 receptor-like protein 3
• Gene ID: 7100
• mRNA Refseq: NM_003268
• Protein Refseq: NP_003259
• MIM: 603031
• UniProt ID: O60602
• Chromosome Location: 1q32.3-q42
• Pathway: Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Legionellosis, organism-specific biosystem; Legionellosis, conserved biosystem; MyD88 cascade initiated on plasma membrane, organism-specific biosystem; Pathogenic Escherichia coli infection, organism-specific biosystem; Pathogenic Escherichia coli infection, conserved biosystem
• Function: interleukin-1 receptor binding; receptor activity