Recombinant Human TLK2

• Cat.No.: TLK2-30422TH
• Product Overview: Recombinant fragment of Human TLK2 with N-terminal proprietary tag expressed in a Baculovirus infected Sf9 insect cell expression system; amino acids 388-772, 67 kDa,

Specification

• Species: Human
• Tag: Non
• Protein Length: 388-772 a.a.
• Description: The Tousled-like kinases, first described in Arabidopsis, are nuclear serine/threonine kinases that are potentially involved in the regulation of chromatin assembly.
• Tissue specificity: Widely expressed. Present in fetal placenta, liver, kidney, pancreas, heart and skeletal muscle. Also found in adult cell lines.
• Biological activity: The specific activity of TLK2-30422TH was determined to be 79 nmol/min/mg
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.Contains 1 protein kinase domain.

Gene Information

• Gene Name: TLK2 tousled-like kinase 2 [ Homo sapiens ]
• Official Symbol: TLK2
• Synonyms: TLK2; tousled-like kinase 2; serine/threonine-protein kinase tousled-like 2; MGC44450; PKU ALPHA
• Gene ID: 11011
• mRNA Refseq: NM_001112707
• Protein Refseq: NP_001106178
• MIM: 608439
• Uniprot ID: Q86UE8
• Chromosome Location: 17q23
• Function: ATP binding; nucleotide binding; protein serine/threonine kinase activity; protein serine/threonine kinase activity