Recombinant Human THBD protein, His-tagged

• Cat.No.: THBD-2743H
• Product Overview: Recombinant Human THBD aa. (Asp325~Asp481 (Accession # P07204)) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Asp325~Asp481
• Description: The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 18.6kDa
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 4.3.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: THBD thrombomodulin [ Homo sapiens (human) ]
• Official Symbol: THBD
• Synonyms: TM; THRM; AHUS6; BDCA3; CD141; THPH12; CD141 antigen; fetomodulin; thrombomodulin
• Gene ID: 7056
• mRNA Refseq: NM_000361.2
• Protein Refseq: NP_000352.1
• UniProt ID: P07204