Recombinant Human TGFBR1 Protein, MYC/DDK-tagged

• Cat.No.: TGFBR1-701H
• Product Overview: Recombinant human TGFBR1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 53.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: transforming growth factor beta receptor 1[ Homo sapiens ]
• Official Symbol: TGFBR1
• Synonyms: AAT5; ACVRLK4; ALK-5; ALK5; ESS1; LDS1; LDS1A; LDS2A; MSSE; SKR4; tbetaR-I; TGFR-1
• Gene ID: 7046
• mRNA Refseq: NM_004612.2
• Protein Refseq: NP_004603.1
• MIM: 190181
• UniProt ID: P36897