Recombinant Human TGFB3 Protein, His-tagged

Cat.No. : TGFB3-2764H
Product Overview : Recombinant Human TGFB3 Protein (Ala301-Ser412) with a N-His tag was expressed in E. coli.
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Species : Human
Source : E.coli
Tag : His
Protein Length : Ala301-Ser412
Description : This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1.
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 16.4 kDa
Accurate Molecular Mass: 17 kDa
Endotoxin : <1.0 EU per 1µg (determined by the LAL method).
Purity : > 95%
Applications : Cell culture; Activity Assays.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Storage Buffer : 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Reconstitution : Reconstitute in 20mM Tris, 150mM NaCl (PH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Gene Name TGFB3 transforming growth factor, beta 3 [ Homo sapiens (human) ]
Official Symbol TGFB3
Synonyms TGFB3; transforming growth factor, beta 3; transforming growth factor beta-3; TGF-beta-3; ARVD; TGF-beta3; FLJ16571;
Gene ID 7043
mRNA Refseq NM_003239
Protein Refseq NP_003230
MIM 190230
UniProt ID P10600

Not For Human Consumption!

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