Recombinant Human TGFB1 protein, His & Avi-tagged

• Cat.No.: TGFB1-137H
• Product Overview: Human Latent TGF beta 1 Protein is expressed from mammalian with His Tag at the N-terminal and Avi Tag at the C-terminal. It contains Leu30-Ser390(C33S mutant)

Specification

• Description: Latent TGF beta 1 cDNA encodes a 390 amino acid precursor that contains a 29 aa signal peptide and a 361 aa proprotein. A furin‑like convertase processes the proprotein to generate an N‑terminal 249 aa latency‑associated peptide (LAP) and a C‑terminal 112 aa mature TGF‑ beta 1. Disulfide‑linked homodimers of LAP and TGF‑ beta 1 remain non‑covalently associated after secretion, forming the small latent TGF‑ beta 1 complex.
• Source: HEK293
• Species: Human
• Tag: His&Avi
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 44.4 KDa.
• Protein length: Leu30-Ser390
• Endotoxin: Less than 1EU per ug by the LAL method.
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: TGFB1 transforming growth factor beta 1[ Homo sapiens (human) ]
• Official Symbol: TGFB1
• Synonyms: Transforming growth factor beta-1 proprotein,Latency-associated peptide, Transforming growth factor beta-1, CEDLAP; DPD1; latency-associated peptide; TGF beta1; TGFB; TGFB1; TGF-beta 1 protein; TGFbeta 1; TGF-beta 1; TGFbeta; TGF-beta-1; transforming growth factor beta-1
• Gene ID: 7040
• mRNA Refseq: NM_000660.7
• Protein Refseq: NP_000651.3
• MIM: 190180
• UniProt ID: P01137