Recombinant Human TFAP2B Protein, His-tagged

• Cat.No.: TFAP2B-586H
• Product Overview: Recombinant Human TFAP2B fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives.
• Form: 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
• Molecular Mass: 50.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) [ Homo sapiens ]
• Official Symbol: TFAP2B
• Synonyms: TFAP2B; transcription factor AP-2 beta (activating enhancer binding protein 2 beta); transcription factor AP 2 beta (activating enhancer binding protein 2 beta); transcription factor AP-2-beta; AP2 B; AP2-beta; activating enhancer binding protein 2 beta; activating enhancer-binding protein 2-beta; AP-2B; AP2-B; MGC21381
• Gene ID: 7021
• mRNA Refseq: NM_003221
• Protein Refseq: NP_003212
• MIM: 601601
• UniProt ID: Q92481