Recombinant Human TBC1D22B, His-tagged

• Cat.No.: TBC1D22B-80H
• Product Overview: Recombinant human TBC1D22B was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: TBC1D22B also known as TBC1 domain family member 22B. TBC1D22B may act as a GTPase-activating protein for Rab family protein. The Tre-2/Bub2/Cdc16 (TBC) domain is a conserved protein motif that consists of approximately 200 amino acids and is thought to function as a specific Rab-GAP domain. The TBC domain is more than 40 distinct TBC domain-containing proteins have been identified in humans.
• Form: Liquid. In Phosphate buffered saline (pH7.4) containing 30% glycerol, 1mM DTT
• Molecular Mass: 61.5kDa (528aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAAENSK QFWKRSAKLP GSIQPVYGAQ HPPLDPRLTK NFIKERSKVN TVPLKNKKAS SFHEFARNTS DAWDIGDDEE EDFSSPSFQT LNSKVALATA AQVLENHSKL RVKPERSQST TSDVPANYKV IKSSSDAQLS RNSSDTCLRN PLHKQQSLPL RPIIPLVARI SDQNASGAPP MTVREKTRLE KFRQLLSSQN TDLDELRKCS WPGVPREVRP ITWRLLSGYL PANTERRKLT LQRKREEYFG FIEQYYDSRN EEHHQDTYRQ IHIDIPRTNP LIPLFQQPLV QEIFERILFI WAIRHPASGY VQGINDLVTP FFVVFLSEYV EEDVENFDVT NLSQDMLRSI EADSFWCMSK LLDGIQDNYT FAQPGIQKKV KALEELVSRI DEQVHNHFRR YEVEYLQFAF RWMNNLLMRE LPLRCTIRLW DTYQSEPEGF SHFHLYVCAA FLIKWRKEIL DEEDFQGLLM LLQNLPTIHW GNEEIGLLLA EAYRLKYMFA DAPNHYRR
• Purity: >80% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: TBC1D22B TBC1 domain family, member 22B [ Homo sapiens ]
• Official Symbol: TBC1D22B
• Synonyms: TBC1D22B; TBC1 domain family, member 22B; C6orf197, chromosome 6 open reading frame 197; TBC1 domain family member 22B; dJ744I24.2; FLJ20337; C6orf197; RP4-744I24.2; MGC125626; MGC125627; DKFZp762J0110
• Gene ID: 55633
• mRNA Refseq: NM_017772
• Protein Refseq: NP_060242
• UniProt ID: Q9NU19
• Chromosome Location: 6p21.2
• Function: GTPase activator activity; Rab GTPase activator activity