Recombinant Human SURF1, His-tagged

• Cat.No.: SURF1-31483TH
• Product Overview: Recombinant fragment of Human SURF1 fused to a 20 amino acid His Tag at N-terminus, 24.3kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 194 amino acids
• Description: This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.
• Conjugation: HIS
• Molecular Weight: 24.300kDa inclusive of tags
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Constituents:0.32% Tris HCl, 0.58% Sodium chloride, 0.02% DTT, 20% Glycerol
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MQVQRRKWKL NLIAELESRV LAEPVPLPAD PMELKNLEYR PVKVRGCFDH SKELYMMPRT MVDPVREARE GGLISSSTQS GAYVVTPFHC TDLGVTILVN RGFVPRKKVN PETRQKGQIE GEVDLIGMVR LTETRQPFVP ENNPERNHWH YRDLEAMARI TGAEPIFIDA NFQSTVPGGP IGGQTRVTLR NEHLQ
• Sequence Similarities: Belongs to the SURF1 family.

Gene Information

• Gene Name: SURF1 surfeit 1 [ Homo sapiens ]
• Official Symbol: SURF1
• Synonyms: SURF1; surfeit 1; surfeit locus protein 1
• Gene ID: 6834
• mRNA Refseq: NM_003172
• Protein Refseq: NP_003163
• MIM: 185620
• Uniprot ID: Q15526
• Chromosome Location: 9q33-q34
• Pathway: Electron Transport Chain, organism-specific biosystem
• Function: cytochrome-c oxidase activity