Recombinant Human Superoxide Dismutase 2, Mitochondrial, GST-tagged

Cat. No. :	SOD2-1636H
Description :	This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Applications :	Western Blot
Molecular Weight :	51 kDa
Species :	Human
Form :	Recombinant protein stored in 50 mM Tris-HCL, pH 7.5, 150 mM NaCl, 0.1 mM PMSF, 0.25 mM DTT, 10 mM gluthione, 0.1 mM EDTA, 25 % glycerol.
Purity :	> 90 %
Concentration :	0.2 ug/ul
Sequences :	Full-length
Storage :	Store product at -70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Name	SOD2 superoxide dismutase 2, mitochondrial [ Homo sapiens ]
Official Symbol	SOD2
Synonyms	SOD2; superoxide dismutase 2, mitochondrial; IPO-B; MNSOD; MVCD6; Mn-SOD; indophenoloxidase B; Mn superoxide dismutase; mangano-superoxide dismutase; manganese-containing superoxide dismutase; EC 1.15.1.1; Superoxide dismutase [Mn], mitochondrial; OTTHUMP00000017530; OTTHUMP00000017531; manganese superoxide dismutase
Gene ID	6648
mRNA Refseq	NM_000636
Protein Refseq	NP_000627
MIM	147460
UniProt ID	P04179
Chromosome Location	6q25.3
Function	manganese ion binding; metal ion binding; oxidoreductase activity; oxygen binding; protein binding; superoxide dismutase activity