Recombinant Human STAMBPL1 Protein (D2-R436), His tagged
Cat.No. : | STAMBPL1-1351S |
Product Overview : | Recombinant Human 6His-TEV-GG-AMSH(S2-R424 end) Protein was expressed in E. coli. |
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Species : | Human |
Source : | E.coli |
Tag : | His |
ProteinLength : | D2-R436 |
Description : | Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains. Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization. Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways. |
Form : | Liquid |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 90% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol |
Shipping : | It is shipped out with blue ice. |
Gene Name | STAMBPL1 STAM binding protein like 1 [ Homo sapiens (human) ] |
Official Symbol | STAMBPL1 |
Synonyms | STAMBPL1; STAM binding protein like 1; AMSH-FP; AMSH-LP; ALMalpha; bA399O19.2; AMSH-like protease; associated molecule with the SH3 domain of STAM (AMSH) - Family Protein; associated molecule with the SH3 domain of STAM (AMSH) like protein; EC 3.1.2.15 |
Gene ID | 57559 |
mRNA Refseq | NM_020799 |
Protein Refseq | NP_065850 |
MIM | 612352 |
UniProt ID | Q96FJ0 |
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Not For Human Consumption!
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