Recombinant Human STAM Protein, MYC/DDK-tagged

Cat.No. : STAM-2850H
Product Overview : Recombinant Human STAM protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
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Species : Human
Source : HEK293
Tag : DDK&Myc
Description : Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 59 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 [ Homo sapiens ]
Official Symbol STAM
Synonyms STAM-1; STAM1
Gene ID 8027
mRNA Refseq NM_003473
Protein Refseq NP_003464
MIM 601899
UniProt ID Q92783

Not For Human Consumption!

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