Recombinant Human ST3GAL1

• Cat.No.: ST3GAL1-29816TH
• Product Overview: Recombinant full length Human SIAT4A with N terminal proprietary tag. Predicted MW 63.47 kDa.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: Non
• Protein Length: 340 amino acids
• Description: The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet.
• Molecular Weight: 63.470kDa inclusive of tags
• Tissue specificity: Expressed in several tissues. Highest expression in lung, liver, skeletal muscle, kidney, pancreas, spleen and placenta.
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the glycosyltransferase 29 family.

Gene Information

• Gene Name: ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [ Homo sapiens ]
• Official Symbol: ST3GAL1
• Synonyms: ST3GAL1; ST3 beta-galactoside alpha-2,3-sialyltransferase 1; sialyltransferase 4A (beta galactosidase alpha 2,3 sialytransferase) , SIAT4A; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1; SIATFL; ST3Gal I; ST3GalA.1; ST3O
• Gene ID: 6482
• mRNA Refseq: NM_173344
• Protein Refseq: NP_775479
• MIM: 607187
• Uniprot ID: Q11201
• Chromosome Location: 8q24.22
• Pathway: Glycosaminoglycan biosynthesis - keratan sulfate, organism-specific biosystem; Glycosaminoglycan biosynthesis - keratan sulfate, conserved biosystem; Glycosphingolipid biosynthesis - ganglio series, organism-specific biosystem; Glycosphingolipid biosynthesis - ganglio series, conserved biosystem; Glycosphingolipid biosynthesis - globo series, organism-specific biosystem
• Function: beta-galactoside (CMP) alpha-2,3-sialyltransferase activity