Recombinant Human SPP1 Protein
| Cat.No. : | SPP1-828H |
| Product Overview : | Recombinant human SPP1 protein without tag was expressed in HEK293. |
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| Description : | The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. |
| Source : | HEK293 |
| Species : | Human |
| Form : | Lyophilized |
| Molecular Mass : | 33 kDa |
| Protein length : | 314 |
| AA Sequence : | MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQNAVSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASSEVN |
| Purity : | > 98% |
| Applications : | Migration Assay; WB; ELISA; |
| Stability : | This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : | At -20 centigrade. |
| Concentration : | 1 mg/mL |
| Storage Buffer : | PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : | Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
| Gene Name | SPP1 secreted phosphoprotein 1 [ Homo sapiens (human) ] |
| Official Symbol | SPP1 |
| Synonyms | SPP1; secreted phosphoprotein 1; OPN; BNSP; BSPI; ETA-1; osteopontin; SPP1/CALPHA1 fusion; early T-lymphocyte activation 1; lnc-PKD2-2-3; nephropontin; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); urinary stone protein; uropontin |
| Gene ID | 6696 |
| mRNA Refseq | NM_000582 |
| Protein Refseq | NP_000573 |
| MIM | 166490 |
| UniProt ID | P10451 |
Not For Human Consumption!
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