Recombinant Human SPHK2 Protein, MYC/DDK-tagged

• Cat.No.: SPHK2-2565H
• Product Overview: Recombinant Human SPHK2 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Description: This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 69 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: SPHK2 sphingosine kinase 2 [ Homo sapiens ]
• Official Symbol: SPHK2
• Synonyms: SK 2; SK-2; SPK 2; SPK-2
• Gene ID: 56848
• mRNA Refseq: NM_001204158
• Protein Refseq: NP_001191087
• MIM: 607092
• UniProt ID: Q9NRA0