Recombinant Human SOX2 protein, MYC/DDK-tagged

• Cat.No.: SOX2-562H
• Product Overview: Recombinant Human SOX2 fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Description: This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 34.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: SOX2 SRY (sex determining region Y)-box 2 [ Homo sapiens ]
• Official Symbol: SOX2
• Synonyms: SOX2; SRY (sex determining region Y)-box 2; transcription factor SOX-2; transcription factor SOX2; SRY-related HMG-box gene 2; ANOP3; MCOPS3; MGC2413
• Gene ID: 6657
• mRNA Refseq: NM_003106
• Protein Refseq: NP_003097
• MIM: 184429
• UniProt ID: P48431
• Chromosome Location: 3q26.3-q27
• Pathway: Wnt Signaling Pathway and Pluripotency, organism-specific biosystem
• Function: DNA binding; DNA binding; miRNA binding; protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding