Recombinant Human SOSTDC1, His-tagged

• Cat.No.: SOSTDC1-7123H
• Product Overview: Recombinant human SOSTDC1 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Specification

• Description: SOSTDC1 is a member of the sclerostin family and an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
• Molecular Mass: 23kDa (206aa)
• Protein length: 24-206aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSFKNDATE ILYSHVVKPV PAHPSSNSTL NQARNGGRHF SNTGLDRNTR VQVGCRELRS TKYISDGQCT SISPLKELVC AGECLPLPVL PNWIGGGYGT KYWSRRSSQE WRCVNDKTRT QRIQLQCQDG STRTYKITVV TACKCKRYTR QHNESSHNFE SMSPAKPVQH HRERKRASKS SKHSMS
• Purity: >85% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml

Gene Information

• Gene Name: SOSTDC1 sclerostin domain containing 1 [ Homo sapiens ]
• Official Symbol: SOSTDC1
• Synonyms: SOSTDC1; sclerostin domain containing 1; sclerostin domain-containing protein 1; DKFZp564D206; ectodin; USAG1; ectodermal BMP inhibitor; cystine-knot containing secreted protein; uterine sensitization-associated protein-1; CDA019; ECTODIN
• Gene ID: 25928
• mRNA Refseq: NM_015464
• Protein Refseq: NP_056279
• MIM: 609675
• UniProt ID: Q6X4U4
• Chromosome Location: 7p21.2
• Pathway: BMP receptor signaling, organism-specific biosystem