Recombinant Human SNX4, His-tagged

Cat.No. : SNX4-31429TH
Product Overview : Recombinant full length protein, corresponding to amino acids 1-450 of Human SNX4 with an N terminal His tag; Predicted MWt 53 kDa.
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Description : This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may form oligomeric complexes with family members.
Conjugation : HIS
Source : E. coli
Form : Lyophilised:Reconstitute with 128 μl aqua dest.
Storage buffer : Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
Storage : Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : MEQAPPDPERQLQPAPLEPLGSPDAGLGAAVGKEAEGAGE ESSGVDTMTHNNFWLKKIEISVSEAEKRTGRNAMNMQE TYTAYLIETRSVEHTDGQSVLTDSLWRRYSEFELLRSY LLVYYPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERR RIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNET GFQLKADSRLKALNATFRVKNPDKRFTDLKHYSDELQS VISHLLRVRARVADRLYGVYKVHGNYGRVFSEWSAIEK EMGDGLQSAGHHMDVYASSIDDILEDEEHYADQLKEYL FYAEALRAVCRKHELMQYDLEMAAQDLASKKQQCEELV TGTVRTFSLKGMTTKLFGQETPEQREARIKVLEEQINEGE QQLKSKNLEGREFVKNAWADIERFKEQKNRDLKEALIS YAVMQISMCKKGIQVWTNAKECFSKM
Sequence Similarities : Belongs to the sorting nexin family.Contains 1 PX (phox homology) domain.
Protein length : 1-450 a.a.
Full Length : Full L.
Gene Name SNX4 sorting nexin 4 [ Homo sapiens ]
Official Symbol SNX4
Synonyms SNX4; sorting nexin 4; sorting nexin-4; ATG24B;
Gene ID 8723
mRNA Refseq NM_003794
Protein Refseq NP_003785
MIM 605931
Uniprot ID O95219
Chromosome Location 3q21.2
Pathway TGF-beta Receptor Signaling Pathway, organism-specific biosystem;
Function lipid binding; phosphatidylinositol binding; protein binding;

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