Recombinant Human SNX15 Protein, MYC/DDK-tagged

• Cat.No.: SNX15-2244H
• Product Overview: Recombinant human SNX15 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293

Specification

• Description: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene. [provided by RefSeq, Dec 2010]
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 38.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: SNX15 sorting nexin 15 [ Homo sapiens ]
• Official Symbol: SNX15
• Synonyms: HSAF001435
• Gene ID: 29907
• mRNA Refseq: NM_013306
• Protein Refseq: NP_037438
• MIM: 605964
• UniProt ID: Q9NRS6