Recombinant Human SNRPD2, His-tagged

• Cat.No.: SNRPD2-3412H
• Product Overview: Recombinant human SNRPD2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: SNRPD2 is a small nuclear ribonucleoprotein (snRNPs) that comprises the spliceosome in eukaryotes. It is required for pre-mRNA splicing and small nuclear ribonucleoprotein biogenesis. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 50% glycerol 0.1M NaCl, 1mM DTT.
• Molecular Weight: 15.6 kDa (138aa) confirmed by MALDI-TOF.
• Purity: > 90% by SDS - PAGE.
• Concentration: 0.25 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MSLLNKPKSE MTPEELQKRE EEEFNTGPLS VLT QSVKNNT QVLINCRNNK KLLGRVKAFD RHCNMVLENVKEMWTEVPKS GKGK KKSKPV NKDRYISKMF LRGDSVIVVL RNPLIAGK.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Pathways: Spliceosome

Gene Information

• Gene Name: SNRPD2 small nuclear ribonucleoprotein D2 polypeptide [ Homo sapiens ]
• Synonyms: SMD2; Sm-D2; SNRPD1; SNRPD2; small nuclear ribonucleoprotein Sm D2; snRNP core protein D2;small nuclear ribonucleoprotein D2 polypeptide; small nuclear ribonucleoprotein D2 polypeptide
• Gene ID: 6633
• mRNA Refseq: NM_004597
• Protein Refseq: NP_004588
• MIM: 601061
• UniProt ID: P62316
• Chromosome Location: 19q13.2
• Function: protein binding