Recombinant Human SNRPC Protein

• Cat.No.: SNRPC-6328H
• Product Overview: Recombinant human SNRPC protein without tag was expressed in E. coli.

Specification

• Description: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
• Source: E. coli
• Species: Human
• Tag: Non
• Form: Lyophilized powder/frozen liquid
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: SNRPC small nuclear ribonucleoprotein polypeptide C [ Homo sapiens (human) ]
• Official Symbol: SNRPC
• Synonyms: SNRPC; small nuclear ribonucleoprotein polypeptide C; U1 small nuclear ribonucleoprotein C; U1 C; Yhc1; U1 snRNP C; U1 snRNP protein C; U1 small nuclear RNP specific C; U1C; FLJ20302
• Gene ID: 6631
• mRNA Refseq: NM_003093
• Protein Refseq: NP_003084
• MIM: 603522
• UniProt ID: P09234