Recombinant Human SNAP29 cell lysate

• Cat.No.: SNAP29-1652HCL

Specification

• Description: This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot
• Tag: Non

Gene Information

• Gene Name: SNAP29 synaptosomal-associated protein, 29kDa [ Homo sapiens ]
• Official Symbol: SNAP29
• Synonyms: SNAP29; synaptosomal-associated protein, 29kDa; synaptosomal associated protein, 29kD; synaptosomal-associated protein 29; CEDNIK; SNAP 29; soluble 29 kDa NSF attachment protein; vesicle-membrane fusion protein SNAP-29; SNAP-29; FLJ21051
• Gene ID: 9342
• mRNA Refseq: NM_004782
• Protein Refseq: NP_004773
• MIM: 604202
• UniProt ID: O95721
• Chromosome Location: 22q11.21
• Pathway: SNARE interactions in vesicular transport, organism-specific biosystem; SNARE interactions in vesicular transport, conserved biosystem
• Function: SNAP receptor activity

Reviews

10/06/2019

it has demonstrated remarkable effectiveness in ELISA experiments, showcasing its reliability and accuracy in detecting and quantifying specific targets.

06/06/2019

The reliable performance of the SNAP29 protein in ELISA and its compatibility with protein electron microscopy structure analysis make it an excellent choice for a wide range of research studies.

06/13/2017

the SNAP29 protein has proven to be an invaluable asset in protein electron microscopy structure analysis.

Q&As

What are the current diagnostic methods for assessing SNAP29-related diseases?

Diagnostic methods include genetic testing to identify mutations in the SNAP29 gene, as well as clinical examinations and imaging studies to assess the manifestation of associated symptoms.

How does SNAP29 protein contribute to vesicle trafficking within cells?

SNAP29 is involved in the assembly of SNARE complexes, which mediate the fusion of transport vesicles with their target membranes, facilitating the trafficking of proteins and lipids within cells.

Can SNAP29 protein be used as a potential therapeutic target for other neurodevelopmental disorders?

Given its role in membrane fusion and intracellular trafficking, SNAP29 is being explored as a potential therapeutic target for other neurodevelopmental disorders characterized by similar cellular defects.

Can SNAP29 protein be used as a therapeutic target for certain diseases?

Yes, research is underway to explore the potential of targeting SNAP29 for the development of new therapeutic interventions for CEDNIK syndrome and related disorders.

How does the SNAP29 protein interact with other cellular components to regulate membrane fusion?

SNAP29 interacts with other SNARE proteins, as well as regulatory proteins and lipids, to orchestrate the fusion of vesicles with target membranes in a regulated and coordinated manner.