Recombinant Human SNAI1 Protein (Met1-Arg264), His tagged

• Cat.No.: SNAI1-3405H
• Product Overview: Recombinant human SNAI1 (Met1-Arg264) protein fused with His tag was expressed in E. coli.

Specification

• Description: The Snail family transcriptional repressor 1 (SNAI1) is known to promote metastatic phenotypes in renal cell carcinoma (RCC). Targeting the miR-211-5p/SNAI1 signaling pathway may be a novel therapeutic approach for the treatment of RCC metastasis. Given its central role in EMT and tumor metastasis, the cell has evolved multiple levels of regulatory mechanism at transcriptional, post-transcriptional, and post-translational level to regulate SNAI1 expression. SNAI1, a zinc-finger transcription factor, plays an important role in the induction of epithelial-mesenchymal transition (EMT) in various cancers.
• Source: E. coli
• Species: Human
• Tag: His
• Molecular Mass: 30.71 kDa
• Protein length: Met1-Arg264
• Purity: >90 % as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: SNAI1 snail homolog 1 (Drosophila) [ Homo sapiens (human) ]
• Official Symbol: SNAI1
• Synonyms: SNAI1; snail homolog 1 (Drosophila); snail 1 (drosophila homolog), zinc finger protein; zinc finger protein SNAI1; SLUGH2; SNA; SNAH; SNAIL; SNAIL1; protein sna; snail 1 homolog; protein snail homolog 1; snail 1 zinc finger protein; snail 1, zinc finger protein; dJ710H13.1
• Gene ID: 6615
• mRNA Refseq: NM_005985
• Protein Refseq: NP_005976
• MIM: 604238
• UniProt ID: O95863