Recombinant Human SMPDL3B Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | SMPDL3B-3075H |
Product Overview : | SMPDL3B MS Standard C13 and N15-labeled recombinant protein (NP_001009568) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Species : | Human |
Source : | HEK293 |
Tag : | DDK&Myc |
Description : | Lipid-modulating phosphodiesterase. Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition and membrane fluidity. Acts as a negative regulator of Toll-like receptor signaling. Has in vitro phosphodiesterase activity, but the physiological substrate is unknown. Lacks activity with phosphocholine-containing lipids, but can cleave CDP-choline, and can release phosphate from ATP and ADP (in vitro). |
Molecular Mass : | 41.7 kDa |
AA Sequence : | MRLLAWLIFLANWGGARAEPGKFWHIADLHLDPDYKVSKDPFQVCPSAGSQPVPDAGPWGDYLCDSPWALINSSIYAMKEIEPEPDFILWTGDDTPHVPDEKLGEAAVLEIVERLTKLIREVFPDTKVYAALGNHDFHPKNQFPAGSNNIYNQIAELWKPWLSNESIALFKKGAFYCEKLPGPSGAGRIVVLNTNLYYTSNALTADMADPGQQFQWLEDVLTDASKAGDMVYIVGHVPPGFFEKTQNKAWFREGFNEKYLKVVRKHHRVIAGQFFGHHHTDSFRMLYDDAGVPISAMFITPGVTPWKTTLPGVVNGANNPAIRVFEYDRATLSLKVRSPAEARGGGWEGLKCITTFPHSQLIHLPLTTEPQEGTRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name | SMPDL3B sphingomyelin phosphodiesterase acid like 3B [ Homo sapiens (human) ] |
Official Symbol | SMPDL3B |
Synonyms | SMPDL3B; sphingomyelin phosphodiesterase, acid-like 3B; acid sphingomyelinase-like phosphodiesterase 3b; ASML3B; ASM-like phosphodiesterase 3b; |
Gene ID | 27293 |
mRNA Refseq | NM_001009568 |
Protein Refseq | NP_001009568 |
MIM | 617737 |
UniProt ID | Q92485 |
◆ Recombinant Proteins | ||
Smpdl3b-3070M | Recombinant Mouse Smpdl3b, His-tagged | +Inquiry |
SMPDL3B-2822H | Recombinant Human SMPDL3B, His-tagged | +Inquiry |
SMPDL3B-3075H | Recombinant Human SMPDL3B Protein, Myc/DDK-tagged, C13 and N15-labeled | +Inquiry |
Smpdl3b-159M | Recombinant Mouse Smpdl3b Protein, MYC/DDK-tagged | +Inquiry |
SMPDL3B-15644M | Recombinant Mouse Smpdl3b Protein, MYC/DDK-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
SMPDL3B-1654HCL | Recombinant Human SMPDL3B 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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