Recombinant Human SLC4A10 Protein (E2-S1118), 8×His-MBP, Flag tagged

• Cat.No.: SLC4A10-1209H
• Product Overview: Recombinant Human 8His-MBP-TEV-(GG)-SLC4A10(E2-S1118)-Flag Protein was expressed in Insect cell.

Specification

• Species: Human
• Source: Insect Cells
• Tag: Flag&His&MBP
• Protein Length: E2-S1118
• Description: Sodium/bicarbonate cotransporter which plays an important role in regulating intracellular pH. Has been shown to act as a sodium/bicarbonate cotransporter in exchange for intracellular chloride. Has also been shown to act as a sodium/biocarbonate cotransporter which does not couple net influx of bicarbonate to net efflux of chloride, with the observed chloride efflux being due to chloride self-exchange. Controls neuronal pH and may contribute to the secretion of cerebrospinal fluid. Reduces the excitability of CA1 pyramidal neurons and modulates short-term synaptic plasticity. Required in retinal cells to maintain normal pH which is necessary for normal vision. In the kidney, likely to mediate bicarbonate reclamation in the apical membrane of the proximal tubules.
• Form: Liquid
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 60%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Formulation:
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: SLC4A10 solute carrier family 4 member 10 [ Homo sapiens (human) ]
• Official Symbol: SLC4A10
• Synonyms: SLC4A10; solute carrier family 4 member 10; NCBE; NBCn2; sodium-driven chloride bicarbonate exchanger; solute carrier family 4, sodium bicarbonate cotransporter-like, member 10; solute carrier family 4, sodium bicarbonate transporter, member 10
• Gene ID: 57282
• mRNA Refseq: NM_022058
• Protein Refseq: NP_071341
• MIM: 605556
• UniProt ID: Q6U841